An innovative bedside genetic test being implemented in Manchester could dramatically improve outcomes for thousands of people in the UK affected by stroke each year. The test can tell healthcare professionals in approximately one hour if stroke patients will be more likely to benefit from clopidogrel, the current first-line treatment to prevent recurrence.
An antibiotic with anti-inflammatory properties will be trialed in 45 stroke units across the UK starting in early 2025. The trial, led by Professor Craig Smith will determine whether this additional treatment will improve clinical and health economic outcomes.
Work on an imaging test to detect and monitor inflammation in brain tumours will take a step forward thanks to two new grants. Researchers within our brain imaging theme are developing a clinically applicable imaging test that could be used in all magnetic resonance imaging (MRI) scanners to help predict tumour growth and guide treatment.
Scientists from our brain tumour theme along with colleagues from the Manchester Centre for Clinical Neurosciences, part of Northern Care Alliance NHS Foundation Trust have published a paper in Neuro-Oncology Advances. It is the first in vivo evidence of increased TSPO expression and inflammation within the brains of patients with growing sporadic vestibular schwannomas.
Manchester is one of nine leading universities which will benefit from a record £35 million funding injection from the British Heart Foundation (BHF) to help strengthen world-leading cardiovascular disease research in the UK. The funding comes from the highly competitive Research Excellence Awards funding scheme.
A team of researchers from The University of Manchester and the Geoffrey Jefferson Brain Research Centre have made an exciting discovery. This important research has been published in the prestigious journal Science Advances and could pave the way for new treatments in the future.
Dementia theme lead Dr Ross Dunne will be overseeing the research team at the Dementia Research Centre and the brainHealth Manchester clinic in the Dementias Platform UK (DPUK) blood biomarker challenge, a project which aims to bring cutting-edge blood tests for diagnosing dementia within the NHS.
An exciting new study is underway working with patients to develop treatments for post-stroke vision impairment. The results will be used for future training to help improve the visual field area after stroke and other brain injuries.
NF2-Related Schwannomatosis is a rare genetic condition affecting 1 in 33,000. Despite its impact, it remains lesser known. Our latest podcast episode shines a light on NF2, making the complex understandable.
The North American Skull Base Society meeting took place in Atlanta from 16-18 February. It was a fantastic forum for learning & discussion across the whole breadth of skull base surgery. Colleagues from the Jeff attended to give invited talks at the meeting.
Geoffrey Jefferson Brain Research Centre
Clinical Sciences Building
Northern Care Alliance
NHS Foundation Trust
Salford
M6 8FJ
Email: GJBRC@manchester.ac.uk
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