The team aims to bring this cutting-edge technology to preclinical stroke research to gain a better understanding of the mechanisms of SD initiation and their involvement in worsening stroke severity. This work will be a crucial first step in the maturity of this technology towards future clinical translation where they anticipate that it will greatly facilitate management of patients in the neuro-intensive care units.
Category: Research
CHOSEN trial results paves the way for a nationwide phase 3 trial
Pneumonia affects around 1 in 12 people after a stroke and increases their chances of death and disability. CHOSEN aimed to determine the feasibility of different oral healthcare treatments, supported by staff education and training, to prevent pneumonia in UK stroke unit care.
Study aims to help preserve hearing in people with vestibular schwannomas
A team of researchers from our centre have started a new pilot study looking at hearing tests for people with vestibular schwannomas (VS).
Study reveals key cause of brain blood flow restriction in vascular dementia
A recent study funded by the British Heart Foundation, has characterised a new mouse model of hypertension induced vascular dementia, showing the two hallmarks of the disease – a reduction in blood flow to the brain and impaired cognitive function.
MRC award to unravel the role of the thalamus in memory
Dr Alex Kafkas, Lecturer in Cognitive Neuroscience in The University of Manchester's Division of Psychology, Communication and Human Neuroscience, and part of our Imaging Theme has been awarded funding from the Medical Research Council along with colleauges Adrian...
New research hopes to improve negative impact of haemorrhagic stroke
Our stroke theme researchers, Catherine Lawrence (PI), Paul Kasher, Stuart Allan and Ben Dickie have been awarded a grant from The Medical Research Council. Modulating cholesterol 25-hydroxylase: a strategy to accelerate haematoma clearance after intracerebral...
From a fish to a dish, how animal alternatives are advancing stroke research
Scientists have developed new models to investigate brain haemorrhage that can replace the use of mammals.
Health Inequalities and Stroke Rapid Literature Review
Health inequalities are unfair differences in health between different groups in society. This Stroke Association commissioned literature review led by our Rehabilitation and Living with Disability theme lead Professor Audrey Bowen, looks at health inequalities and stroke as a first step to finding out what research exists on health inequalities across the stroke pathway, and collated these studies.
Reducing Inflammation In The Brain After Stroke – Professor Stuart Allan
Professor Stuart Allan is at the forefront of stroke recovery research and is leading a team of researchers working on the next generation of clot-busting medication. Find out more in this episode of the Recovery After Stroke podcast.
Pioneering study targets brain tumours with radiotherapy before surgery
“The POBIG study is a team effort, working alongside neurosurgeons, oncologists, nurses, radiologists, physicists, and pathologists, and importantly patient support groups like the Brainstrust. Besides the novelty of irradiating the tumour before surgery, other innovative aspects are that we base the diagnosis on imaging so as not to delay the treatment. Crucially we don’t irradiate the whole tumour, only the part where the neurosurgeon believes the remnants will be left behind. This prevents interference with the standard clinical pathway of looking into specific tumour characteristics and offers unique opportunities to develop more personalised treatment strategies against this life-limiting disease. We are very pleased with how Joel has responded to this treatment and the result so far is very encouraging. We are hopeful this technique could improve outcomes for all patients like Joel in the future.”
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