
Reducing Inflammation In The Brain After Stroke – Professor Stuart Allan
Professor Stuart Allan is at the forefront of stroke recovery research and is leading a team of researchers working on the next generation of clot-busting medication. Find out more in this episode of the Recovery After Stroke podcast.

Pioneering study targets brain tumours with radiotherapy before surgery
“The POBIG study is a team effort, working alongside neurosurgeons, oncologists, nurses, radiologists, physicists, and pathologists, and importantly patient support groups like the Brainstrust. Besides the novelty of irradiating the tumour before surgery, other innovative aspects are that we base the diagnosis on imaging so as not to delay the treatment. Crucially we don’t irradiate the whole tumour, only the part where the neurosurgeon believes the remnants will be left behind. This prevents interference with the standard clinical pathway of looking into specific tumour characteristics and offers unique opportunities to develop more personalised treatment strategies against this life-limiting disease. We are very pleased with how Joel has responded to this treatment and the result so far is very encouraging. We are hopeful this technique could improve outcomes for all patients like Joel in the future.”

Join us for our Brain Health Day event
The Stroke-IMPaCT team are organising an event called Brain Health Day! Researchers who work on the Stroke-IMPaCT Project will be in attendance, as well as other scientists from the Geoffrey Jefferson Brain Research Centre doing research into other conditions such as Brain Tumours.

NanoSeminar Series 26/01, Prof Simona Parrinello (glioblastoma, UCL Cancer Institute)
Professor Simona Parrinello (UCL Cancer Institute) will be giving a talk about the Glioblastoma and the GEMM preclinical models she has developed. This will be a hybrid event and will take place at the Michael Smith Lecture Theatre, University of Manchester, on the 26/01 at 14:30.

Improving treatments for Parkinson’s disease
A major research project to help improve treatments for Parkinson’s disease will take place at Manchester Metropolitan University, Northern Care Alliance NHS Foundation Trust (NCA) and the Walton Centre (NHS Trust Centre for Neurology and Neurosurgery) in Liverpool. The project will be led by, investigator in our centre’s Parkinson’s theme, Professor Nicola Ray, Manchester Metropolitan’s Department of Psychology and her Co-Investigators at the NCA, Walton Centre and The University of Manchester. Professor Ray developed the ideas for the project from work she and the team have undertaken with funding from Health Innovation Manchester.

Double success for GJBRC researchers
Funding has been awarded through the dual-award PhD programme between the University of Melbourne and University of Manchester. The dual-award scheme brings together research teams between the two institutions with a PhD student assigned to each. This is a highly competitive scheme with just six dual awards (twelve students) made across both Universities in all disciplines. For our researchers to secure two of these awards is therefore a fantastic achievement.

Latest updates on movement disorders
The Association of British Neurologists’ Movement Disorders Special Interest Group meeting will come to Manchester for the first time in January 2023.

Imaging the blood-brain barrier after stroke
Post-stroke cognitive decline is one of the most distressing complications in stroke survivors, occurring in up to a third of those affected by stroke within five years. Laura Parkes, Craig Smith and Stuart Allan have been awarded funding to track changes in the brain over months and years in people who have suffered a stroke. The Imaging Hub will be based in Manchester, with $780k funding for research scans and an imaging scientist to work with Dr Parkes and her team.

Hema’s half marathon
Hema Mistry successfully ran the Manchester Half Marathon on Sunday 9 October. Hema finished the race in a very impressive 2:05 raising over £900 for vascular dementia research in our centre.

Outstanding research impact results
The Research Excellence Framework is the system for assessing the quality of research in UK higher education institutions, including research impact, the research environment, research publications and other outputs. One of the high-scoring impact case studies was led by Prof Audrey Bowen, who leads the Centre’s research theme – Rehabilitation and Living with Disability.
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